The nicotinic acetylcholine receptor Champix is available in tablet form. Different strengths are available, including 0.5mg and 1mg of varenicline per tablet. Usually, Champix is taken for 12 weeks for the best effect. It's important to use it properly, or else you may suffer severe withdrawal symptoms.
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How Does Champix Work?
What does it do? Champix works by causing the release of dopamine. This simulates the effects of cigarette smoking. For many, Champix also lowers the enjoyment of smoking, making it much easier to quit.
Champix's active ingredient, varenicline, acts as a full or partial agonist for nicotinic acetylcholine receptors. Through this mechanism of action, it lowers the effectiveness of nicotine to bind to the mesolimbic dopamine system. This makes further smoking significantly less addictive and enjoyable.
How to take Champix? It's recommended to get medical advice on how to use Champix most efficiently for your situation. Usually, it's taken for 12 or more weeks once or twice per day. The dosage will vary, and it's important to follow your doctor's instructions to prevent overdosing.
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Side Effects of Champix
When you commence taking Champix, you may experience two sets of negative effects. Quitting smoking can be difficult, and adverse events can sometimes occur.
Potential withdrawal symptoms include:
- Cravings for another smoke, which will intensify at times.
- Mood swings, anger, minor depression, anxiety, irritability, and other emotional modifications you may not be expecting.
- Weight gain (not weight loss), greater appetite, and difficulty managing your weight.
- Sleeplessness, restlessness, and concentration issues, particularly if you consume large amounts of caffeine (a stimulant found in coffee, some soft drinks, energy drinks, and other foods and beverages).
- Light-headedness or dizziness.
In some cases, you may also experience side effects of your Champix consumption, particularly with long-term use.
- Mild nausea occurs in an estimated 30 percent of people on Champix.
- A slightly increased risk of adverse cardiovascular events, such as a heart attack, may be present.
- There's a very low risk of serious effects such as seizures, sleepwalking, oral blisters, chest pains, and localized numbness.
Other inconsequential side effects include toothaches, abnormal menstrual cycles, constipation, heartburn, and headache. Report to your GP if you're worried about any side effects or overdose.
Contraindications of the Medication
Various medical conditions and other medicines are contraindicated with varenicline. Avoid taking Champix pills or any generic variations if you suffer any of the following:
- Schizophrenia or similar mental illnesses.
- Alcoholism or severe alcohol consumption.
- Angina or acute coronary syndrome.
- Manic-depression and similar illnesses.
- Renal impairment reducing the efficacy of the kidneys.
- Peripheral vascular disease.
This is by no means an exhaustive list, so speak with your doctor if you suffer any other conditions.
There are a few medications that are known to interact with varenicline. Minor interactions may be experienced with cimetidine and lamotrigine, while moderate interactions are possible with ethanol (alcohol), nicotine (cigarettes), vandetanib, dalfampridine, ranolazine, and dolutegravir. Seek professional advice before taking Champix or other varenicline medicine with and of the above-listed treatments and substances.
Champix Smoking Cessation Medication FAQs
Below are a few noteworthy questions and answers about Champix.
What is Champix's principle of action?
Champix binds to nicotinic acetylcholine receptors, causing the release of dopamine. Its elimination half-life is approximately 24 hours, less than 10% is metabolised, and 81 to 92% is excreted through the kidneys.
How much is Champix to purchase online?
Prices vary dependent on your purchase volume and current rates. However, we deliver competitively priced, budget-friendly Champix.
Can it be used during pregnancy?
It is usually not recommended. It should also be avoided during breastfeeding, not to mention that smoking itself is harmful for a fetus and baby.
Is Champix good for weight loss?
No, taking Champix and quitting smoking in general usually leads to gaining weight, becoming heavier than you perhaps would like. There are reports of Champix leading to weight loss, but these are rare.