Purchase Metronidazole (Flagyl) Over the Counter Safely
It's available in 200 mg, 250 mg, 400 mg and 500 mg doses. Generic Flagyl can be purchased through our class A online store. This is an oral medicine, and its uses stretch across a broad spectrum of applications. Other formats on the market include cream, gel, spray, etc.
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What Is Flagyl (Metronidazole) 400mg Dosage Used for?
What does Flagyl treat? As an antibiotic, antiprotozoal medication, Flagyl is used to treat various infections and other conditions. It's a bitter substance, and the correct dose is usually administered as a pill or via a liquid containing metronidazole benzoate. Illnesses commonly treated include:
- Aspiration pneumonia.
- Lung abscesses, which involve liquefactive necrosis of lung tissue.
- Amoebiasis, also known as amoebic dysentery, caused by infection with Entamoeba histolytica parasites.
- Trichomoniasis, an STI triggered by the Trichomonas vaginalis parasite.
- Pseudomembranous colitis, caused by the Clostridium difficule bacteria.
- Chlamydia and other STDs.
- Giardiasis, a disease caused by Giardia lamblia (also known as Giardia intestinalis) bacteria.
- Fungating wounds.
Metronidazole (Flagyl) in 400mg and other dosages is commonly used to treat bacterial vaginosis (BV). It may be taken in pill form or administered vaginally (as suppositories) once per day for five days. This is a debilitating disease resulting in fishy-smelling vaginal discharge and localised burning sensations.
Similarly, it's an acceptable treatment for pelvic inflammatory disease. This affects the upper female reproductive system, including the ovaries, fallopian tubes, and uterus. Symptoms include infertility, ectopic pregnancy, and irregular menstruation.
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How Quickly Does Metronidazole Work?
Metronidazole's mechanism of action supports rapid working times. In healthy adults, the half-life is just eight to ten hours. The substance has more than 80% bioavailability and it's absorbed via the gut and digestive tract. Excretion is via the kidneys and faeces. Peak metronidazole blood concentrations occur within one to two hours following consumption.
Your doctor or medical advisor will specify the most appropriate dosage rate and frequency. In most cases, Flagyl is taken once to twice per day, and many courses have a duration of one to ten days. The most common Flagyl therapy duration is around seven days.
Symptoms may vanish promptly, but it's paramount to persist until your scheduled pills run out, or else your infection may return. Premature discontinuation or termination of your medication may lead to bacterial resistance, which can cause major health problems in the future.
Metronidazole: Contraindications With Alcohol and Other Substances
Metronidazole is contraindicated with a scattering of some other medications. Be careful taking Flagyl or other metronidazole-based pills if you're taking any of the following, or else interactions could occur:
- Cyclosporin (immune system dampener)
- Warfarin (blood thinner)
- Fluorouracil or busulfan (cancer medications)
- Disulfiram (alcoholism treatment)
- Lithium (mental health maintenance)
- Phenobarbitone or phenytoin (epilepsy treatment)
Flagyl is heavily contraindicated with alcohol. Unfortunately, you will have to abstain from your favourite cocktails and other drinks while taking it. Otherwise, serious side effects such as hot flushes, heart palpitations, and headaches can occur. You shouldn't drink until at least two days following your final dose.
Pregnancy is a common contraindication with antibiotic medications. But in this case, it's usually safe to take metronidazole while pregnant (except the first trimester) or breastfeeding. The gestational use of oral or vaginally applied metronidazole may actually have some benefits. There have been many studies in the field. Reports suggest that treating bacterial vaginosis with metronidazole is effective in reducing the risk of preterm birth.
Does Flagyl Have Noteworthy Side Effects?
Using Flagyl to treat bacterial infections does have some side effects. Common effects include headaches, diarrhea, nausea, stomatitis, glossitis, genital pruritus, moniliasis, rhinitis, myalgia, skin rashes, and pharyngitis. There are also various more serious and very rare side effects to be aware of, including:
- Encephalopathy, a form of brain damage caused by an adverse reaction to Flagyl.
- Increased risk of bacterial meningitis and inflammation around the brain.
- Peripheral neuropathy, a condition affecting your nerves and reducing movement and feeling in the extremities.
When combined with mebendazole, metronidazole is reported to cause Stevens-Johnson syndrome, a severe skin reaction that can cause epidermal necrolysis. What's more, studies on rats and mice suggest that metronidazole may be carcinogenic, however, due to inadequate epidemiological evidence, it's considered safe for humans in this regard. It's recommended that you only take it when necessary.